Natural herb extract sennosides 20% Senna Leaf Extract CAS NO.517-43-1

senna leaf extract powder

The active ingredient in senna extract powder is called sennoside. The laxative effect of sennoside and its active metabolite rhein anthrone is believed to inhibit the absorption of water and electrolyte in the large intestine, thereby increasing the volume and pressure of intestinal contents. It will stimulate the push-type tightening movement of the colon.senna extract powder the Sennoside can be prepared as enema or suppository or mixed with stool softener or lumpy fibrous laxative to form a combined laxative.

The laxative effect of sennoside and its active metabolite rhein anthrone are thought to inhibit the absorption of water and electrolyte in the large intestine, thereby increasing the volume and pressure of the intestinal contents. It will stimulate the push-type tightening movement of the colon. In addition, the stimulating effect on the secretion of active chloride increases the content of intestinal water and electrolyte. These changes in the transport of active electrolyte depend on calcium on the surface of the serous membrane. The laxative effect of sennoside is partly through the stimulation of colonic fluid and electrolyte secretion, and the secretion ability is regulated by the stimulation of the formation of endogenous prostaglandins. Sennoside can be prepared as an enema or suppository or mixed with a stool softener or a lumpy fiber laxative to form a combined laxative.